INTS6 anticorps (AA 750-800)

N° du produit ABIN7448519

L’anticorps Lapin Polyclonal anti-INTS6 a été validé pour IHC. Il convient pour détecter INTS6 dans des échantillons de Humain.

Aperçu rapide pour INTS6 anticorps (AA 750-800) (ABIN7448519)

Antigène: INTS6 (Integrator Complex Subunit 6 (INTS6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INTS6 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-INTS6 anticorps

Épitope: AA 750-800

Fonction: Rabbit anti-DDX26/DICE1 IHC Antibody, Affinity Purified

Homologie: Bovine,Horse,Rabbit,Pig,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Tasmanian devil,African elephant,Northern white-cheeked gibbon,Gray short-tailed opossum

Purification: Affinity Purified

Immunogène: Between AA 750 and 800

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur INTS6

Antigène: INTS6 (Integrator Complex Subunit 6 (INTS6))

Autre désignation: DDX26/DICE1

Sujet: Background: DDX26/DICE1 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX26/DICE1 is a subunit of the integrator complex involved in 3'-end processing of snRNAs. DDX26/DICE1 is implicated as a tumor suppressor, and its ectopic expression has been shown to inhibit tumor cell growth. Alternative names for DDX26/DICE1 include integrator complex subunit 6, Int6, protein deleted in cancer 1, protein DDX26, DBI-1, deleted in cancer 1, INTS6, DDX26A, HDB, Nochl2, and DKFZP434B105.

ID gène: 26512

NCBI Accession: NP_036273

UniProt: Q9UL03