DDX5 anticorps (C-Term)

N° du produit ABIN7448522

L’anticorps Lapin Polyclonal anti-DDX5 a été validé pour IHC. Il convient pour détecter DDX5 dans des échantillons de Humain et Souris.

Aperçu rapide pour DDX5 anticorps (C-Term) (ABIN7448522)

Antigène: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX5 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-DDX5 anticorps

Épitope: C-Term

Fonction: Rabbit anti-DDX5 IHC Antibody, Affinity Purified

Homologie: Rat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Tasmanian devil,Bonnet macaque,White-tufted-ear marmoset,Gray short-tailed opossum,Little brown bat,African elephant,Chinese hamster,Northern white-cheeked gibbon,Duckbill platypus,Thirteen-lined ground squirrel,Naked mole rat

Purification: Affinity Purified

Immunogène: Between AA 575 and C-term

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DDX5

Antigène: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Autre désignation: DDX5

Sujet: Background: DDX5 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. In addition to a role involved in RNA splicing, DDX5 has been observed to interact with and act as a transcriptional coactivator for estrogen receptor alpha (ERalpha). DDX5 has also been found to interact with CBP/300, Smad3, and p53 to modulate transcription. DDX5 is closely related to and forms heterodimers with DDX17.

ID gène: 1655

NCBI Accession: NP_004387

UniProt: P17844

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus