DGCR8 anticorps (AA 1-50)

N° du produit ABIN7448526

Cet anticorps anti-DGCR8 est un anticorps Lapin Polyclonal détectant DGCR8 dans IHC. Adapté pour Humain.

Aperçu rapide pour DGCR8 anticorps (AA 1-50) (ABIN7448526)

Antigène: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DGCR8 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-DGCR8 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-DGCR8 IHC Antibody, Affinity Purified

Homologie: Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Crab-eating macaque

Purification: Affinity Purified

Immunogène: Between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DGCR8

Antigène: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Autre désignation: DGCR8

Sujet: Background: DiGeorge syndrome critical region 8 (DGCR8) is a component of the microprocessor complex that acts as a RNA- and heme-binding protein and is involved in the initial step of microRNA (miRNA) biogenesis. DGCR8 functions as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junctions. It directs RNASEN/DROSHA to cleave 11 bp away from the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs [taken from the Universal Protein Resource (UniProt) Q8WYQ5].

ID gène: 54487

NCBI Accession: NP_073557

UniProt: Q8WYQ5

Pathways: Regulatory RNA Pathways