Rad6 (N-Term) anticorps

N° du produit ABIN7448752

Cet anticorps Lapin Polyclonal détecte spécifiquement dans IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Rad6 (N-Term) anticorps (ABIN7448752)

Antigène: Rad6

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC)

Détail du produit

Épitope: N-Term

Fonction: Rabbit anti-Rad6 IHC Antibody, Affinity Purified

Homologie: Rat,D. melanogaster,Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Atlantic salmon,Tasmanian devil,Rainbow smelt,Rainbow trout,Nile tilapia,Ferret,Yeast_237561,Killifish,African elephant,Medaka fish,Thirteen-lined ground squirrel,Yeast_284593,Zebra finch,Little brown bat,Teleostei,Small-eared galago,Japanese pufferfish,Naked mole rat,Green anole,Northern white-cheeked gibbon,Sablefish,Red sea bream,Northern pike,West Indian ocean coelacanth,Baker's yeast_559292,Spotted green pufferfish,Three-spined stickleback,Yeast_284811,Yeast_284590

Purification: Affinity Purified

Immunogène: N-terminus

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détail du antigène

Antigène: Rad6

Sujet: Background: Rad 6, also known as Ubiquitin conjugating enzyme E2A, is an E2 enzyme of the three step ubiquitination pathway. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ubiquitination provides an important post-translational means to regulate protein abundance and activity. Rad6 has been demonstrated to be important to DNA damage repair. Mutations in Rad6 cause an X-linked mental retardation syndrome.

ID gène: 7319

NCBI Accession: NP_003327

UniProt: P49459