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Stock
4 °C
Date de péremption
12 months
Antigène
RANGAP1
(Ran GTPase Activating Protein 1 (RANGAP1))
Autre désignation
RanGAP1
Sujet
Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.