RNF20 anticorps (AA 125-175)

N° du produit ABIN7448779

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF20 dans IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour RNF20 anticorps (AA 125-175) (ABIN7448779)

Antigène: RNF20 (Ring Finger Protein 20 (RNF20))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF20 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-RNF20 anticorps

Épitope: AA 125-175

Fonction: Rabbit anti-RNF20 IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Crab-eating macaque,White-tufted-ear marmoset,Tasmanian devil,Gray short-tailed opossum,Small-eared galago,Naked mole rat,Thirteen-lined ground squirrel,Chinese hamster,Northern white-cheeked gibbon,Green anole,Zebra finch,Ferret,Little brown bat

Purification: Affinity Purified

Immunogène: Between AA 125 and 175

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur RNF20

Antigène: RNF20 (Ring Finger Protein 20 (RNF20))

Autre désignation: RNF20

Sujet: Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ring finger protein 20 (RNF20) is a member of the RING type E3 ubiquitin ligases. RNF20 forms a complex with RNF40 to carry out H2B monoubiquitination in association with hPAF and the UbcH6 ubiquitin E2-conjugating enzyme. H2B monoubiquitination by RNF40/RNF20 has been shown to be associated with increased H3 methylation and gene transcription.

ID gène: 56254

NCBI Accession: NP_062538

UniProt: Q5VTR2