ZEB2 anticorps (AA 750-800)

N° du produit ABIN7448878

Cet anticorps Lapin Polyclonal détecte spécifiquement ZEB2 dans IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ZEB2 anticorps (AA 750-800) (ABIN7448878)

Antigène: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZEB2 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-ZEB2 anticorps

Épitope: AA 750-800

Fonction: Rabbit anti-ZEB2/SIP IHC Antibody, Affinity Purified

Homologie: Bovine,Dog,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Ferret,White-tufted-ear marmoset,Thirteen-lined ground squirrel,Small-eared galago,Naked mole rat,Crab-eating macaque,Northern white-cheeked gibbon,Little brown bat

Purification: Affinity Purified

Immunogène: Between AA 750 and 800

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ZEB2

Antigène: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Autre désignation: ZEB2/SIP

Sujet: Background: Smad interacting protein 1 (SIP1) is a transcriptional inhibitor that binds to the DNA sequence, 5'-CACCT-3', in different promoters. SIP1 has been shown to repress the transcription of E-cadherin. Defects in the gene which encodes for SIP1, ZEB2, are the cause of Hirschsprung disease-mental retardation syndrome (Hirschsprung disease) also known as Mowat-Wilson syndrome (MWS). Hirschsprung disease is a rare autosomal dominant complex developmental disorder [taken from the Universal Protein Resource (UniProt) O60315].

ID gène: 9839

NCBI Accession: NP_055610

UniProt: O60315

Pathways: Tube Formation