CHD8 anticorps (AA 2252-2302)

N° du produit ABIN7448888

L’anticorps Lapin Polyclonal anti-CHD8 a été validé pour IHC. Il convient pour détecter CHD8 dans des échantillons de Humain.

Aperçu rapide pour CHD8 anticorps (AA 2252-2302) (ABIN7448888)

Antigène: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHD8 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-CHD8 anticorps

Épitope: AA 2252-2302

Fonction: Rabbit anti-CHD8 IHC Antibody, Affinity Purified

Homologie: Mouse,Bovine,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Tasmanian devil,Crab-eating macaque,Naked mole rat,Small-eared galago,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Little brown bat,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogène: Between AA 2252 and 2302

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CHD8

Antigène: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Autre désignation: CHD8

Sujet: Background: CHD8 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD8 has been reported to interact with duplin, a protein involved in the wnt signaling pathway, and CTCF, a protein involved in heterochromatin formation.

ID gène: 57680

NCBI Accession: NP_065971

UniProt: Q9HCK8

Pathways: Chromatin Binding