Merlin anticorps (C-Term)

N° du produit ABIN7448991

Cet anticorps anti-Merlin est un anticorps Lapin Polyclonal détectant Merlin dans IHC et IF (p). Adapté pour Humain.

Aperçu rapide pour Merlin anticorps (C-Term) (ABIN7448991)

Antigène: Merlin (NF2) (Neurofibromin 2 (NF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Merlin est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Merlin anticorps

Épitope: C-Term

Fonction: Rabbit anti-NF2 IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine,Dog,Horse,Rabbit,Pig,Panda,Orangutan,Gorilla,Chinese hamster,White-tufted-ear marmoset,Olive baboon,African elephant,Northern white-cheeked gibbon,Ferret,Naked mole rat,Thirteen-lined ground squirrel

Purification: Affinity Purified

Immunogène: Between AA 550 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Merlin

Antigène: Merlin (NF2) (Neurofibromin 2 (NF2))

Autre désignation: NF2

Sujet: Background: Mutations in NF2 (neurofibromin 2) are associated with neurofibromatosis type II which is characterized by Schwann cell tumors (schwannomas) which are benign slow-growing tumors that are resistant to chemotherapeutic intervention. NF2 is a membrane/cytoskeletal associated protein that has been classified as a novel type of tumor suppressor due to its function in membrane organization versus a classic tumor suppressor function that regulates cell cycle machinery.

ID gène: 4771

NCBI Accession: NP_000259

UniProt: P35240

Pathways: Cell-Cell Junction Organization