WDR77 anticorps (AA 292-342)

N° du produit ABIN7449034

Cet anticorps Lapin Polyclonal détecte spécifiquement WDR77 dans IHC et IF (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour WDR77 anticorps (AA 292-342) (ABIN7449034)

Antigène: WDR77 (WD Repeat Domain 77 (WDR77))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR77 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-WDR77 anticorps

Épitope: AA 292-342

Fonction: Rabbit anti-WDR77/MEP50 IHC Antibody, Affinity Purified

Homologie: Orangutan,Monkey,Chimpanzee,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogène: Between AA 292 and 342

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur WDR77

Antigène: WDR77 (WD Repeat Domain 77 (WDR77))

Autre désignation: WDR77/MEP50

Sujet: Background: WDR77/MEP50 is a component of the methylosome, a large protein arginine methyltransferase complex that modifies specific arginines to dimethylarginines in splicesomal Sm proteins. WDR77/MEP50 associates with the methyltransferase JBP1 (PRMT5) and is important for methylosome activity. WDR77/MEP50 has also been shown to associate with the polycomb group protein, SUZ12, and histone H2A. In this context, WDR77/MEP50 is proposed to function as an adaptor between PRMT5 and its substrate H2A to regulate transcription.

ID gène: 79084

NCBI Accession: NP_077007

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization