KIF20B anticorps (AA 825-875)

N° du produit ABIN7449101

Détail du produit anti-KIF20B anticorps

Antigène: KIF20B (Kinesin Family Member 20B (KIF20B))

Épitope: AA 825-875

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF20B est non-conjugé

Application: Immunoprecipitation (IP)

Fonction: Rabbit anti-KIF20B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 825 and 875

Isotype: IgG

Information d'application

Indications d'application: 8 - 15 μL/mg lysate

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KIF20B

Antigène: KIF20B (Kinesin Family Member 20B (KIF20B))

Autre désignation: KIF20B (KIF20B Produits)

Synonymes: anticorps ct90, anticorps mpp1, anticorps krmp1, anticorps mpp-1, anticorps MGC83846, anticorps mphosph1, anticorps KIF20B, anticorps MPHOSPH1, anticorps CT90, anticorps KRMP1, anticorps MPP-1, anticorps MPP1, anticorps B130024C23, anticorps C330014J10Rik, anticorps Mphosph1, anticorps kinesin family member 20B S homeolog, anticorps kinesin family member 20B, anticorps kif20b.S, anticorps KIF20B, anticorps kif20b, anticorps Kif20b

Sujet: Background: Kinesin family member 20B (KIF20B) is a plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). KIF20B is required for proper midbody organization and abscission in polarized cortical stem cells. It plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. KIF20B participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, KIF20B cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. It is involved in cerebral cortex growth (By similarity). KIF20B acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [taken from the Universal Protein Resource (UniProt) Q96Q89].

ID gène: 9585

UniProt: Q96Q89

Pathways: M Phase