Syntaxin 17 anticorps (AA 100-150)
Aperçu rapide pour Syntaxin 17 anticorps (AA 100-150) (ABIN7449144)
Antigène
Voir toutes Syntaxin 17 (STX17) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 100-150
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Fonction
- Rabbit anti-STX17 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- Between AA 100 and 150
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Isotype
- IgG
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Indications d'application
- 8 - 15 μL/mg lysate
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- Syntaxin 17 (STX17)
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Autre désignation
- STX17
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Sujet
- Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane (PubMed:23217709, PubMed:25686604). May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355) [taken from the Universal Protein Resource (UniProt) P56962].
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ID gène
- 55014
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UniProt
- P56962
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Pathways
- Synaptic Vesicle Exocytosis
Antigène
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