Cet anticorps anti-Syntaxin 17 Polyclonal Lapin (ABIN7449144) détecte spécifiquement Syntaxin 17 dans IP.
L’anticorps est réactif avec des échantillons de Humain.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Date de péremption
12 months
Antigène
Syntaxin 17 (STX17)
Autre désignation
STX17
Sujet
Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane (PubMed:23217709, PubMed:25686604). May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355) [taken from the Universal Protein Resource (UniProt) P56962].