FLG2 anticorps (AA 100-150)
Aperçu rapide pour FLG2 anticorps (AA 100-150) (ABIN7449193)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 100-150
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Fonction
- Rabbit anti-FLG2 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 100 and 150
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Isotype
- IgG
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Indications d'application
- 1:10,000 - 1:25,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- FLG2 (Filaggrin Family Member 2 (FLG2))
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Autre désignation
- FLG2
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Sujet
- Background: The FLG2 protein is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. FLG2 is also required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa. [provided by RefSeq, Dec 2015] [taken from NCBI Entrez Gene (Gene ID: 388698)].
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ID gène
- 388698
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UniProt
- Q5D862
Antigène
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