SETDB1 anticorps (AA 1125-1175)

N° du produit ABIN7449256

Cet anticorps Lapin Polyclonal détecte spécifiquement SETDB1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SETDB1 anticorps (AA 1125-1175) (ABIN7449256)

Antigène: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETDB1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SETDB1 anticorps

Épitope: AA 1125-1175

Fonction: Rabbit anti-SETDB1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1125 and 1175

Isotype: IgG

Information d'application

Indications d'application: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SETDB1

Antigène: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Autre désignation: SETDB1

Sujet: Background: SETDB1 (SET domain, bifurcated 1) is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family that functions as a histone and DNA methyltransferase. SETDB1 was identified through its interaction with ERG (ets-related gene) and KAP1 (KRAB-associated protein1) and was later demonstrated to interact with HDAC1/2 (histone deacetylase 1/2), DNA methyltransferase 3s (DNMT3s), mSin3A/3B, HP1, and MBD1. SETDB1 is suggested to play a role in transcriptional repression important to early development.

ID gène: 9869

NCBI Accession: NP_036564

UniProt: Q15047