P4HTM anticorps (C-Term)

N° du produit ABIN7449275

L’anticorps Lapin Polyclonal anti-P4HTM a été validé pour WB. Il convient pour détecter P4HTM dans des échantillons de Humain.

Aperçu rapide pour P4HTM anticorps (C-Term) (ABIN7449275)

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P4HTM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-P4HTM anticorps

Épitope: C-Term

Fonction: Rabbit anti-PHD4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 450 and C-term

Isotype: IgG

Information d'application

Indications d'application: 1:500 - 1:2,500

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur P4HTM

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Autre désignation: PHD4

Sujet: Background: PHD4 is one of 4 PHD (PHD1-4) enzymes that function as oxygen sensors and are responsible for the post-translational modification of HIF-1alpha, a component of a transcriptional complex involved in oxygen homeostasis. During normoxic levels, PHDs catalyze the hydroxylation of prolyl residues on HIF-1alpha and target it for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. The PHD isoforms appear to function in a non-redundant manner and may differ in their expression patterns and their catalytic selectivity.

ID gène: 54681

NCBI Accession: NP_808808

UniProt: Q9NXG6