CSN2 anticorps (AA 1-50)

N° du produit ABIN7449364

Cet anticorps Lapin Polyclonal détecte spécifiquement CSN2 dans WB et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CSN2 anticorps (AA 1-50) (ABIN7449364)

Antigène: CSN2 (Casein beta (CSN2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSN2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CSN2 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-CSN2 Antibody, Affinity Purified

Homologie: Rat,Zebrafish,X. laevis

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CSN2

Antigène: CSN2 (Casein beta (CSN2))

Autre désignation: CSN2

Sujet: Background: CSN2 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals a function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN2 has also been demonstrated to interact with the sin3A corepressor complex as well as the thyroid hormone and vitamin D3 receptor to mediate gene repression.

ID gène: 9318

NCBI Accession: NP_004227

UniProt: P61201