Recombinant CD56 anticorps (AA 20-318)

N° du produit ABIN7449431

L’anticorps Lapin Monoclonal anti-CD56 a été validé pour WB, IHC et ICC. Il convient pour détecter CD56 dans des échantillons de Humain.

Aperçu rapide pour Recombinant CD56 anticorps (AA 20-318) (ABIN7449431)

Antigène: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD56 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR152J

Détail du produit anti-CD56 anticorps

Épitope: AA 20-318

Fonction: Rabbit anti-NCAM-1/CD56 Recombinant Monoclonal Antibody [BLR152J]

Immunogène: residues 20-318 (ECD)

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CD56

Antigène: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Autre désignation: NCAM-1/CD56

Sujet: Background: NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)].

ID gène: 4684

NCBI Accession: NP_000606

UniProt: P13591