CD45RO anticorps

N° du produit ABIN7449553

Cet anticorps Souris Monoclonal détecte spécifiquement CD45RO dans FACS, IHC, WB, IF (p), ICC et mIF. Il présente une réactivité envers Humain.

Aperçu rapide pour CD45RO anticorps (ABIN7449553)

Antigène: CD45RO

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD45RO est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)

Clone: UCHL-1

Détail du produit anti-CD45RO anticorps

Fonction: Mouse anti-CD45RO Monoclonal Antibody Purified [UCHL-1]

Purification: Purified

Immunogène: Cultured T-cells from an IL-2-dependent T-cell line (CA1)

Isotype: IgG2a

Information d'application

Indications d'application:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 05:10:00

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 50 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur CD45RO

Antigène: CD45RO

Autre désignation: CD45RO

Sujet: CD45 is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45 recruits and dephosphorylates SKAP1 and FYN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08575].

ID gène: 5788

UniProt: P08575