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CD45RO anticorps

CD45RO Reactivité: Humain WB, IHC, IF (p), ICC, mIF Hôte: Souris Monoclonal UCHL-1 unconjugated

N° du produit ABIN7449553

Fiche de données

Antigène Tous les produits CD45RO

CD45RO
Reactivité
75

12

12

11

11
Humain
Hôte
63

12
Souris
Anticorps secondaires appropriés
Clonalité
63

12
Monoclonal
Conjugué
11

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD45RO est non-conjugé
Application
58

29

25

13

12

10

10

9

4

3

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)

Fonction

Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]

Immunogène

Cultured T-cells from an IL-2-dependent T-cell line (CA1)

Clone

UCHL-1

Isotype

IgG
anti-CD45RO (CD45RO) antibody
CD45RO Reactivité: Humain, Souris, Rat WB, IHC (p), IF (p) Hôte: Lapin Polyclonal unconjugated

anti-CD45RO (CD45RO) antibody
GMP Grade CD45RO Reactivité: Humain FACS, IHC, IP Hôte: Souris Monoclonal UCHL1 unconjugated

anti-CD45RO (CD45RO) antibody (FITC)
GMP Grade CD45RO Reactivité: Humain FACS Hôte: Souris Monoclonal UCHL1 FITC

anti-CD45RO (CD45RO) antibody (PE)
GMP Grade CD45RO Reactivité: Humain FACS Hôte: Souris Monoclonal UCHL1 PE

anti-CD45RO (CD45RO) antibody (mFluor™450)
GMP Grade CD45RO Reactivité: Humain FACS Hôte: Souris Monoclonal UCHL1 mFluor™450

anti-CD45RO (CD45RO) antibody (APC)
GMP Grade CD45RO Reactivité: Humain FACS Hôte: Souris Monoclonal UCHL1 APC

anti-CD45RO (CD45RO) antibody (PE-CF®594)
GMP Grade CD45RO Reactivité: Humain FACS Hôte: Souris Monoclonal UCHL1 PE-CF®594

anti-CD45RO (CD45RO) antibody (PE-Cy7)
CD45RO Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal UCHL1 PE-Cy7

anti-CD45RO (CD45RO) antibody
CD45RO Reactivité: Humain, Chimpanzé, Marmoset FACS, IF, IHC (p) Hôte: Souris Monoclonal UCHL-1 unconjugated

anti-CD45RO (CD45RO) antibody (FITC)
CD45RO Reactivité: Humain FACS Hôte: Souris Monoclonal UCHL1 FITC

Indications d'application

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 05:10:00

Restrictions

For Research Use only
Concentration

50 μg/mL

Buffer

Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C

Date de péremption

12 months
Antigène

CD45RO

Autre désignation

CD45RO (CD45RO Produits)

Sujet

Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].

ID gène

5788

NCBI Accession

NP_002829

UniProt

P08575