Merlin anticorps (C-Term)

N° du produit ABIN7449601

Cet anticorps Lapin Polyclonal détecte spécifiquement Merlin dans WB et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour Merlin anticorps (C-Term) (ABIN7449601)

Antigène: Merlin (NF2) (Neurofibromin 2 (NF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Merlin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Merlin anticorps

Épitope: C-Term

Fonction: Rabbit anti-NF2 Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: between AA 550 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 1 - 4 μg/mg lysate

WB: 1:5,000 - 1:15,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Merlin

Antigène: Merlin (NF2) (Neurofibromin 2 (NF2))

Autre désignation: NF2

Sujet: Background: Mutations in NF2 (neurofibromin 2) are associated with neurofibromatosis type II which is characterized by Schwann cell tumors (schwannomas) which are benign slow-growing tumors that are resistant to chemotherapeutic intervention. NF2 is a membrane/cytoskeletal associated protein that has been classified as a novel type of tumor suppressor due to its function in membrane organization versus a classic tumor suppressor function that regulates cell cycle machinery.

ID gène: 4771

NCBI Accession: NP_057502

UniProt: P35240

Pathways: Cell-Cell Junction Organization