HRPT2 anticorps (AA 250-300)
Aperçu rapide pour HRPT2 anticorps (AA 250-300) (ABIN7449603)
Antigène
Voir toutes HRPT2 (CDC73) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 250-300
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Fonction
- Rabbit anti-Parafibromin Antibody, Affinity Purified
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Homologie
- Rat
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Purification
- Affinity Purified
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Immunogène
- between AA 250 and 300
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Isotype
- IgG
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Indications d'application
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IP: 1 - 4 μg/mg lysate
WB: 1:5,000 - 1:20,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- HRPT2 (CDC73) (Parafibromin (CDC73))
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Autre désignation
- Parafibromin
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Sujet
- Background: Parafibromin, also known as HRPT2 (hyperparathyroidism 2 protein), has been identified as a tumor suppressor that is associated with hyperparathyroidism-jaw tumor syndrome, an autosomal dominant disease characterized by hyperparathyroidism due to parathyroid tumors and ossifying fibromas of the mandible and maxilla. Parafibromin is a component of the PAF1 complex that associates with RNA polymerase II and plays a role in mRNA 3'-end processing and transcription elongation. Parafibromin has been demonstrated to function as an inhibitor of the cell cycle.
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ID gène
- 79577
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NCBI Accession
- NP_078805
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UniProt
- Q6P1J9
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
Antigène
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