Ataxin 1 anticorps (AA 350-400)

N° du produit ABIN7449649

Cet anticorps Lapin Polyclonal détecte spécifiquement Ataxin 1 dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour Ataxin 1 anticorps (AA 350-400) (ABIN7449649)

Antigène: Ataxin 1 (ATXN1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ataxin 1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-Ataxin 1 anticorps

Épitope: AA 350-400

Fonction: Rabbit anti-Ataxin-1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 350 and 400

Isotype: IgG

Information d'application

Indications d'application:

IP: 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-Ataxin-1 antibody A302-292A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Ataxin 1

Antigène: Ataxin 1 (ATXN1)

Autre désignation: Ataxin-1

Sujet: Background: Defects in ataxin-1 are the cause of spinocerebellar ataxia type 1 (SCA1), also known as olivopontocerebellar atrophy I (OPCA I or OPCA1). Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to cerebellum degeneration with variable involvement of the brainstem and spinal cord. SCA1 is caused by expansion of a CAG repeat in the coding region of the ataxin-1 gene. Longer expansions result in earlier onset and more severe clinical manifestations of the disease. Ataxin-1 binds RNA in vitro and may be involved in RNA metabolism [taken from the Universal Protein Resource (UniProt) P54253].

ID gène: 6310

NCBI Accession: NP_000323

UniProt: P54253

Pathways: Synaptic Membrane