DHX36 anticorps (C-Term)

N° du produit ABIN7449716

L’anticorps anti-DHX36 Polyclonal Lapin est utilisé pour la détection de DHX36 dans des échantillons de Humain et Souris. Il a été validé pour WB et IP.

Aperçu rapide pour DHX36 anticorps (C-Term) (ABIN7449716)

Antigène: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX36 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-DHX36 anticorps

Épitope: C-Term

Fonction: Rabbit anti-DHX36 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 950 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DHX36

Antigène: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Autre désignation: DHX36

Sujet: Background: DHX36 is a member of the DEAH box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DHX36 expression is highest in testis and plays a role in 3'-5' degradation of AU-rich RNAs. Interestingly, DHX36 has also been observed to function as a G4-DNA resolvase. In this capacity DHX36 catalyzes the resolution of highly stable G4- DNA structures that form in guanine-rich regions of single-stranded DNA.

ID gène: 170506

NCBI Accession: NP_065916

UniProt: Q9H2U1

Pathways: Toll-Like Receptors Cascades