FOXM1 anticorps (AA 713-763)

N° du produit ABIN7449736

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXM1 dans WB et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour FOXM1 anticorps (AA 713-763) (ABIN7449736)

Antigène: FOXM1 (Forkhead Box M1 (FOXM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXM1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-FOXM1 anticorps

Épitope: AA 713-763

Fonction: Rabbit anti-FOXM1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 713 and 763

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FOXM1

Antigène: FOXM1 (Forkhead Box M1 (FOXM1))

Autre désignation: FOXM1

Sujet: Background: FOXM1 belongs to a large family of Forkhead transcription factors that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). It is a transcription factor critical to cell cycle progression via its role in coordinating the G2/M phase transition. FOXM1 is ubiquitously expressed in proliferating cells but is absent in differentiated cells. FOXM1 overexpression has been detected in a variety of tumor types including breast, lung, prostate, and liver cancer, and appears to be involved in tumorigenesis-associated processes such as angiogenesis and metastasis. In light of these findings, FOXM1 has recently become an attractive target for anti-cancer therapy.

ID gène: 2305

NCBI Accession: NP_973731

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus