Afadin anticorps (AA 1475-1525)

N° du produit ABIN7449949

Cet anticorps Lapin Polyclonal détecte spécifiquement Afadin dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Afadin anticorps (AA 1475-1525) (ABIN7449949)

Antigène: Afadin (MLLT4)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Afadin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Afadin anticorps

Épitope: AA 1475-1525

Fonction: Rabbit anti-AF6 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1475 and 1525

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Afadin

Antigène: Afadin (MLLT4)

Autre désignation: AF6

Sujet: Background: AF6 was identified as part of a fusion with MLL (mixed lineage leukemia) in a t(6,11) genetic translocation. AF6 is also known as afadin (a splicing variant of AF6 found at adherins junction). AF6/afadin is an actin filament binding protein that binds to nectin at cadherin-based cell-cell adherens junctions and regulates cell-cell adhesion by mediating Ras signaling.

ID gène: 4301

UniProt: P55196

Pathways: Cell-Cell Junction Organization