F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1321-1371) anticorps
Aperçu rapide pour F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1321-1371) anticorps (ABIN7450068)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1321-1371
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Fonction
- Rabbit anti-CARMIL Antibody, Affinity Purified
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Homologie
- Mouse
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Purification
- Affinity Purified
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Immunogène
- Between AA 1321 and 1371
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- F-Actin-Uncapping Protein LRRC16A (CARMIL1)
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Autre désignation
- CARMIL
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Sujet
- Background: CARMIL binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. It increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. CARMIL Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).CARMIL may control actin dynamics in lamellipodi and be required for cell migration [taken from the Universal Protein Resource (UniProt) Q5VZK9].
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ID gène
- 55604
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NCBI Accession
- NP_060110
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UniProt
- Q5VZK9
Antigène
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