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F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1321-1371) anticorps

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans IP et WB. Adapté pour Humain.
N° du produit ABIN7450068

Aperçu rapide pour F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1321-1371) anticorps (ABIN7450068)

Antigène

F-Actin-Uncapping Protein LRRC16A (CARMIL1)

Reactivité

Humain

Hôte

  • 4
Lapin

Clonalité

  • 4
Polyclonal

Conjugué

  • 1
  • 1
  • 1
  • 1
Inconjugué

Application

Immunoprecipitation (IP), Western Blotting (WB)
  • Épitope

    AA 1321-1371

    Fonction

    Rabbit anti-CARMIL Antibody, Affinity Purified

    Homologie

    Mouse

    Purification

    Affinity Purified

    Immunogène

    Between AA 1321 and 1371

    Isotype

    IgG
  • Indications d'application

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions

    For Research Use only
  • Concentration

    1000 μg/mL

    Buffer

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Date de péremption

    12 months
  • Antigène

    F-Actin-Uncapping Protein LRRC16A (CARMIL1)

    Autre désignation

    CARMIL

    Sujet

    Background: CARMIL binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. It increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. CARMIL Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).CARMIL may control actin dynamics in lamellipodi and be required for cell migration [taken from the Universal Protein Resource (UniProt) Q5VZK9].

    ID gène

    55604

    NCBI Accession

    NP_060110

    UniProt

    Q5VZK9
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