CDK13 anticorps (AA 1125-1175)

N° du produit ABIN7450096

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK13 dans WB et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour CDK13 anticorps (AA 1125-1175) (ABIN7450096)

Antigène: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK13 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-CDK13 anticorps

Épitope: AA 1125-1175

Fonction: Rabbit anti-CDC2L5 Antibody, Affinity Purified

Homologie: Mouse,Bovine

Purification: Affinity Purified

Immunogène: between AA 1125 and 1175

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CDK13

Antigène: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Autre désignation: CDC2L5

Sujet: Background: CDC2-like kinase 5 (CDC2L5) is a member of the cyclin-dependent serine/threonine protein kinase family that plays a central role in cell cycle control. The CDC2L5 cDNA was first identified as CHED (cholinesterase-related cell-division controller) and cloned serendipitously in a screen using a cholinesterase-specific oligonucleotide probe in search of a link between cholinergic signaling and hematopoietic cell division control. Recently, the understanding of the physiological function of CDC2L5 has become clearer. Due to its localization to speckles in the nucleoplasm and its interaction with the splicing protein, ASF/SF2-associated protein p32, it was suggested to play a role in mRNA processing. Further studies showed that overexpression of CDC2L5 altered mRNA splicing patterns, and that CDC2L5 associated with L-type cyclins known to be involved in alternative splicing. These results have led to the conclusion that CDC2L5 is part of a subfamily of cyclin dependent kinases that play a role in the regulation of alternative splicing.

ID gène: 8621

NCBI Accession: NP_003709

UniProt: Q14004