EPC1 anticorps (AA 325-375)

N° du produit ABIN7450211

Détail du produit anti-EPC1 anticorps

Antigène: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Épitope: AA 325-375

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPC1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-EPC1 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 325 and 375

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur EPC1

Antigène: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Autre désignation: EPC1 (EPC1 Produits)

Synonymes: anticorps EPC1, anticorps Epl1, anticorps 2400007E14Rik, anticorps 5730566F07Rik, anticorps A930032N02Rik, anticorps epc1, anticorps enhancer of polycomb homolog 1, anticorps enhancer of polycomb homolog 1 (Drosophila) a, anticorps enhancer of polycomb homolog 1 (Drosophila), anticorps enhancer of polycomb homolog 1 L homeolog, anticorps EPC1, anticorps epc1a, anticorps Epc1, anticorps epc1, anticorps epc1.L

Sujet: Background: Enhancer of polycomb homolog 1 (EPC1) is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage [taken from the Universal Protein Resource (UniProt) Q9H2F5].

ID gène: 80314

NCBI Accession: NP_079485

UniProt: Q9H2F5

Pathways: Regulation of Muscle Cell Differentiation