ISR-beta anticorps (AA 1332-1382)

N° du produit ABIN7450366

Cet anticorps Lapin Polyclonal détecte spécifiquement ISR-beta dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ISR-beta anticorps (AA 1332-1382) (ABIN7450366)

Antigène: ISR-beta (Insulin Receptor beta (ISR-beta))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISR-beta est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-ISR-beta anticorps

Épitope: AA 1332-1382

Fonction: Rabbit anti-Insulin Receptor Beta Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 1332 and 1382

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ISR-beta

Antigène: ISR-beta (Insulin Receptor beta (ISR-beta))

Autre désignation: Insulin Receptor Beta

Sujet: Background: The insulin receptor is a receptor tyrosine kinase that mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates to stimulate uptake of glucose. The insulin receptor is synthesized as a single polypeptide that is cleaved to generate an alpha and beta subunit. The subunit structure of the insulin receptor consists of a tetramer of two alpha and two beta chains linked by disulfide bonds.

ID gène: 3643

NCBI Accession: NP_000199

UniProt: P06213