ZBTB33 anticorps (AA 622-672)

N° du produit ABIN7450384

Détail du produit anti-ZBTB33 anticorps

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Épitope: AA 622-672

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB33 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-Kaiso Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 622 and 672

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur ZBTB33

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Autre désignation: Kaiso (ZBTB33 Produits)

Synonymes: anticorps kaiso, anticorps ZNF-kaiso, anticorps ZNF348, anticorps AW260253, anticorps E130014G12Rik, anticorps Kaiso, anticorps Znf-kaiso, anticorps RGD1566309, anticorps zinc finger and BTB domain containing 33 S homeolog, anticorps zinc finger and BTB domain containing 33, anticorps zbtb33.S, anticorps ZBTB33, anticorps Zbtb33

Sujet: Background: Transcriptional regulator Kaiso possesses bimodal DNA-binding specificity and binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. Kaiso contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Kaiso may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. [taken from NCBI Entrez Gene (Gene ID: 10009)].

ID gène: 10009

NCBI Accession: NP_006768

UniProt: Q86T24