MAP4K4 anticorps (AA 850-900)
Aperçu rapide pour MAP4K4 anticorps (AA 850-900) (ABIN7450432)
Antigène
Voir toutes MAP4K4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 850-900
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Fonction
- Rabbit anti-MAP4K4/HGK Antibody, Affinity Purified
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Homologie
- Mouse
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Purification
- Affinity Purified
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Immunogène
- between AA 850 and 900
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Isotype
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibody
MAP4K4 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 4A5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 866-1104) antibodyMAP4K4 Reactivité: Humain WB, ELISA, IF, IHC Hôte: Lapin Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) antibodyMAP4K4 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB1895 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivité: Humain, Souris, Rat WB, ELISA, IF, IHC, ICC Hôte: Lapin Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 287-336) antibodyMAP4K4 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Porc, Roussette (Chauve-souris), Poulet, Xenopus laevis WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 400-500) antibodyMAP4K4 Reactivité: Humain ELISA Hôte: Souris Monoclonal 4H9E7 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibodyMAP4K4 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2D4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (N-Term) antibodyMAP4K4 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivité: Humain, Souris WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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Autre désignation
- MAP4K4/HGK
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Sujet
- Background: MAP4K4 is a serine/threonine kinase that signals upstream of the c-Jun N-terminal kinase (JNK) and is involved in cell motility. MAP4K4 appears to partially mediate TNF alpha signaling. In skeletal muscle TNF-alpha induces insulin resistance. TNF-alpha induced insulin resistance has been shown to be dependent on MAPK4K4 activity. Interestingly, TNF-alpha regulates MAP4K4 expression and can stimulate MAP4K4 gene expression via TNFR2 (TNFalpha receptor 2) and the c-Jun and ATF2 (activating transcription factor 2) transcription factors. MAP4K4 is highly expressed in most tumor cell lines, and the analysis of MAP4K4 mutants indicates that it may have an important role in cell transformation and invasiveness.
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ID gène
- 9448
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UniProt
- O95819
Antigène
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