MUM1 anticorps (AA 125-175)

N° du produit ABIN7450469

L’anticorps anti-MUM1 Polyclonal Lapin est utilisé pour la détection de MUM1 dans des échantillons de Humain. Il a été validé pour WB et IP.

Aperçu rapide pour MUM1 anticorps (AA 125-175) (ABIN7450469)

Antigène: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUM1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-MUM1 anticorps

Épitope: AA 125-175

Fonction: Rabbit anti-MUM1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 125 and 175

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MUM1

Antigène: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Autre désignation: MUM1

Sujet: Background: Mutated melanoma-associated antigen 1 (MUM1) is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. MUM1 is recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. MUM1 is required for efficient DNA repair and cell survival following DNA damage [taken from the Universal Protein Resource (UniProt) Q2TAK8].

ID gène: 84939

NCBI Accession: NP_116242

UniProt: Q2TAK8

Pathways: Chromatin Binding