NUP85 anticorps (AA 575-625)
Aperçu rapide pour NUP85 anticorps (AA 575-625) (ABIN7450515)
Antigène
Voir toutes NUP85 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 575-625
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Fonction
- Rabbit anti-NUP85 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- Between AA 575 and 625
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- NUP85 (Nucleoporin 85kDa (NUP85))
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Autre désignation
- NUP85
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Sujet
- Background: Nucleoporin 85 (NUP85) is an essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex, it plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2 and seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade [taken from the Universal Protein Resource (UniProt) Q9BW27].
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ID gène
- 79902
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NCBI Accession
- NP_079120
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UniProt
- Q9BW27
Antigène
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