PKC eta anticorps (AA 633-683)

N° du produit ABIN7450569

Cet anticorps anti-PKC eta est un anticorps Lapin Polyclonal détectant PKC eta dans WB et IP. Adapté pour Humain.

Aperçu rapide pour PKC eta anticorps (AA 633-683) (ABIN7450569)

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC eta est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-PKC eta anticorps

Épitope: AA 633-683

Fonction: Rabbit anti-PKC-eta Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: Between AA 633 and 683

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PKC eta

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Autre désignation: PKC-eta

Sujet: Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC-eta is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. PKC-eta can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene [taken from NCBI Entrez Gene (Gene ID: 5583)].

ID gène: 5583

NCBI Accession: NP_006246

UniProt: P24723

Pathways: Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling