Plexin A3 anticorps (AA 1050-1100)
Aperçu rapide pour Plexin A3 anticorps (AA 1050-1100) (ABIN7450574)
Antigène
Voir toutes Plexin A3 (PLXNA3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1050-1100
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Fonction
- Rabbit anti-Plexin-A3 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- Between AA 1050 and 1100
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- Plexin A3 (PLXNA3)
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Autre désignation
- Plexin-A3
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Sujet
- Background: Plexin-A3 is a coreceptor for SEMA3A and SEMA3F. It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plexin-A3 plays a role in axon guidance in the developing nervous system. It regulates the migration of sympathetic neurons, but not of neural crest precursors. Plexin-A3 is required for normal dendrite spine morphology in pyramidal neurons. It may play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm [taken from the Universal Protein Resource (UniProt) P51805].
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ID gène
- 55558
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NCBI Accession
- NP_059984
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UniProt
- P51805
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Pathways
- Regulation of Cell Size
Antigène
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