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Plexin A3 anticorps (AA 1050-1100)

L’anticorps Lapin Polyclonal anti-Plexin A3 a été validé pour WB et IP. Il convient pour détecter Plexin A3 dans des échantillons de Humain.
N° du produit ABIN7450574

Aperçu rapide pour Plexin A3 anticorps (AA 1050-1100) (ABIN7450574)

Antigène

Voir toutes Plexin A3 (PLXNA3) Anticorps
Plexin A3 (PLXNA3)

Reactivité

  • 26
  • 12
  • 9
Humain

Hôte

  • 27
  • 1
  • 1
Lapin

Clonalité

  • 29
Polyclonal

Conjugué

  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Plexin A3 est non-conjugé

Application

  • 13
  • 13
  • 7
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • Épitope

    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1050-1100

    Fonction

    Rabbit anti-Plexin-A3 Antibody, Affinity Purified

    Purification

    Affinity Purified

    Immunogène

    Between AA 1050 and 1100

    Isotype

    IgG
  • Indications d'application

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions

    For Research Use only
  • Concentration

    1000 μg/mL

    Buffer

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Date de péremption

    12 months
  • Antigène

    Plexin A3 (PLXNA3)

    Autre désignation

    Plexin-A3

    Sujet

    Background: Plexin-A3 is a coreceptor for SEMA3A and SEMA3F. It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plexin-A3 plays a role in axon guidance in the developing nervous system. It regulates the migration of sympathetic neurons, but not of neural crest precursors. Plexin-A3 is required for normal dendrite spine morphology in pyramidal neurons. It may play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm [taken from the Universal Protein Resource (UniProt) P51805].

    ID gène

    55558

    NCBI Accession

    NP_059984

    UniProt

    P51805

    Pathways

    Regulation of Cell Size
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