MPRIP anticorps (AA 400-450)

N° du produit ABIN7450660

Cet anticorps Lapin Polyclonal détecte spécifiquement MPRIP dans WB et IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MPRIP anticorps (AA 400-450) (ABIN7450660)

Antigène: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPRIP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-MPRIP anticorps

Épitope: AA 400-450

Fonction: Rabbit anti-RIP3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 400 and 450

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MPRIP

Antigène: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Autre désignation: RIP3

Sujet: Background: Receptor-interacting serine/threonine-protein kinase 3 (RIP3) is essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIP3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIP3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production [taken from the Universal Protein Resource (UniProt) Q9Y572].

ID gène: 11035

NCBI Accession: NP_006862

UniProt: Q9Y572