RNF20 anticorps (AA 1-50)
Aperçu rapide pour RNF20 anticorps (AA 1-50) (ABIN7450665)
Antigène
Voir toutes RNF20 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-50
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Fonction
- Rabbit anti-RNF20 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 1 and 50
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- RNF20 (Ring Finger Protein 20 (RNF20))
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Autre désignation
- RNF20
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Sujet
- Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ring finger protein 20 (RNF20) is a member of the RING type E3 ubiquitin ligases. RNF20 forms a complex with RNF40 to carry out H2B monoubiquitination in association with hPAF and the UbcH6 ubiquitin E2-conjugating enzyme. H2B monoubiquitination by RNF40/RNF20 has been shown to be associated with increased H3 methylation and gene transcription.
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ID gène
- 56254
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NCBI Accession
- NP_062538
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UniProt
- Q5VTR2
Antigène
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