SHARPIN anticorps (AA 25-75)

N° du produit ABIN7450727

L’anticorps anti-SHARPIN Polyclonal Lapin est utilisé pour la détection de SHARPIN dans des échantillons de Humain. Il a été validé pour WB et IP.

Aperçu rapide pour SHARPIN anticorps (AA 25-75) (ABIN7450727)

Antigène: SHARPIN (SHANK-Associated RH Domain Interacting Protein (SHARPIN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHARPIN est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-SHARPIN anticorps

Épitope: AA 25-75

Fonction: Rabbit anti-SHARPIN Antibody, Affinity Purified

Homologie: Bovine

Purification: Affinity Purified

Immunogène: between AA 25 and 75

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SHARPIN

Antigène: SHARPIN (SHANK-Associated RH Domain Interacting Protein (SHARPIN))

Autre désignation: SHARPIN

Sujet: Background: Sharpin (Shank-associated RH domain-interacting protein) is a component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways [taken from the Universal Protein Resource (UniProt) Q9H0F6].

ID gène: 81858

NCBI Accession: NP_112236

UniProt: Q9H0F6