SKP2 anticorps (AA 1-50)

N° du produit ABIN7450734

Cet anticorps anti-SKP2 est un anticorps Lapin Polyclonal détectant SKP2 dans WB et IP. Adapté pour Humain.

Aperçu rapide pour SKP2 anticorps (AA 1-50) (ABIN7450734)

Antigène: SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKP2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-SKP2 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-SKP2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SKP2

Antigène: SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))

Autre désignation: SKP2

Sujet: Background: S-phase kinase-associated protein 2 (SKP2) is a member of the F-box family of proteins. It is the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. SKP2 specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition [taken from the Universal Protein Resource (UniProt) Q13309].

ID gène: 6502

NCBI Accession: NP_005974

UniProt: Q13309

Pathways: Mitotic G1-G1/S Phases