ThPok (AA 200-250) anticorps
Aperçu rapide pour ThPok (AA 200-250) anticorps (ABIN7450820)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 200-250
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Fonction
- Rabbit anti-ThPOK Antibody, Affinity Purified
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Homologie
- Mouse
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Purification
- Affinity Purified
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Immunogène
- Between AA 200 and 250
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- ThPok
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Sujet
- Background: ThPOK is a transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. ThPOK is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. [taken from the Universal Protein Resource (UniProt) O15156].
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ID gène
- 51043
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NCBI Accession
- NP_056956
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UniProt
- O15156
Antigène
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