Cadherin 13 anticorps (AA 475-525)

N° du produit ABIN7451103

Cet anticorps anti-Cadherin 13 est un anticorps Lapin Polyclonal détectant Cadherin 13 dans IP. Adapté pour Humain.

Aperçu rapide pour Cadherin 13 anticorps (AA 475-525) (ABIN7451103)

Antigène: Cadherin 13 (CDH13)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 13 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-Cadherin 13 anticorps

Épitope: AA 475-525

Fonction: Rabbit anti-Cadherin 13/CDH13/T-cadherin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 475 and 525

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451103 has not performed satisfactorily when used for WB of Cadherin 13/CDH13/T-cadherin in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Cadherin 13/CD.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Cadherin 13

Antigène: Cadherin 13 (CDH13)

Autre désignation: Cadherin 13/CDH13/T-cadherin

Sujet: Background: Cadherin-13 is a member of the cadherin superfamily. Cadherin-13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. Cadherin-13 lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. Cadherin-13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis [taken from NCBI Entrez Gene (Gene ID: 1012)].

ID gène: 1012

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization