Multidrug-Resistance Like Protein 1 anticorps (AA 275-325)

N° du produit ABIN7451476

Cet anticorps Lapin Polyclonal détecte spécifiquement Multidrug-Resistance Like Protein 1 dans IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Multidrug-Resistance Like Protein 1 anticorps (AA 275-325) (ABIN7451476)

Antigène: Multidrug-Resistance Like Protein 1 (MRP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Multidrug-Resistance Like Protein 1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-Multidrug-Resistance Like Protein 1 anticorps

Épitope: AA 275-325

Fonction: Rabbit anti-MRP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 275 and 325

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Multidrug-Resistance Like Protein 1

Antigène: Multidrug-Resistance Like Protein 1 (MRP)

Autre désignation: MRP1

Sujet: Background: Multidrug resistance-associated protein 1 (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. MRP1 functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. MRP1 also transports glucuronides and sulfate conjugates of steroid hormones and bile salts [taken from NCBI Entrez Gene (Gene ID: 4363)].

ID gène: 4363

NCBI Accession: NP_004987

UniProt: P33527