NIPBL anticorps (AA 550-600)

N° du produit ABIN7451484

Cet anticorps anti-NIPBL est un anticorps Lapin Polyclonal détectant NIPBL dans IP. Adapté pour Humain.

Aperçu rapide pour NIPBL anticorps (AA 550-600) (ABIN7451484)

Antigène: NIPBL (Nipped-B like Protein (NIPBL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NIPBL est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-NIPBL anticorps

Épitope: AA 550-600

Fonction: Rabbit anti-NIPBL Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 550 and 600

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NIPBL

Antigène: NIPBL (Nipped-B like Protein (NIPBL))

Autre désignation: NIPBL

Sujet: Background: The NIPBL (Nipped B-like) gene was originally identified as a gene mutated in individuals with Cornelia de Lange syndrome (CdLS), a heterogenous developmental disorder associated with multiple anatomical malformations. The NIPBL protein product is also referred to as delangin. It has substantial homology to the D. melanogaster Nipped-B protein which is related to a family of chromosomal adherins that plays a role in sister chromatid adhesion, chromosome condensation, and DNA repair. A study of metaphase spreads from individuals positive and negative for NIPBL mutations revealed an association between NIPBL mutations and precocious sister chromatid separation. This result suggests a function for NIPBL that is similar to its homolog in drosophila.

ID gène: 25836

NCBI Accession: NP_597677

UniProt: Q6KC79

Pathways: Sensory Perception of Sound, Stem Cell Maintenance