UBXN1 anticorps (AA 262-312)

N° du produit ABIN7451534

L’anticorps Lapin Polyclonal anti-UBXN1 a été validé pour IP. Il convient pour détecter UBXN1 dans des échantillons de Humain.

Aperçu rapide pour UBXN1 anticorps (AA 262-312) (ABIN7451534)

Antigène: UBXN1 (UBX Domain Protein 1 (UBXN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBXN1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-UBXN1 anticorps

Épitope: AA 262-312

Fonction: Rabbit anti-UBXN1 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine

Purification: Affinity Purified

Immunogène: between AA 262 and 312

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur UBXN1

Antigène: UBXN1 (UBX Domain Protein 1 (UBXN1))

Autre désignation: UBXN1

Sujet: Background: UBX domain-containing protein 1 (UBXN1) is a ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. The interaction between UBXN1 and autoubiquitinated BRCA1, leads to the inhibition the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. UBXN1 is also a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.3 kDa protein, UBXD10, 2B28, and SAKS1.

ID gène: 51035

NCBI Accession: NP_056937

UniProt: Q04323