DAB2IP anticorps (AA 950-1000)

N° du produit ABIN7451727

Cet anticorps anti-DAB2IP Polyclonal Lapin (ABIN7451727) détecte spécifiquement DAB2IP dans WB et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DAB2IP anticorps (AA 950-1000) (ABIN7451727)

Antigène: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAB2IP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-DAB2IP anticorps

Épitope: AA 950-1000

Fonction: Rabbit anti-DAB2IP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 950 and 1000

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur DAB2IP

Antigène: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Autre désignation: DAB2IP

Sujet: Background: DAB2-interacting protein (DAB2IP) functions as a Ras GTPase-activating protein. Through its interaction with MAP3K5, it disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. DAB2IP also Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. DAB2IP may act as a tumor suppressor gene [taken from the Universal Protein Resource (UniProt) Q5VWQ8].

ID gène: 153090

UniProt: Q5VWQ8

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation