KIF2C anticorps (C-Term)

N° du produit ABIN7451865

Cet anticorps anti-KIF2C est un anticorps Lapin Polyclonal détectant KIF2C dans WB et IP. Adapté pour Humain.

Aperçu rapide pour KIF2C anticorps (C-Term) (ABIN7451865)

Antigène: KIF2C (Kinesin Family Member 2C (KIF2C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF2C est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-KIF2C anticorps

Épitope: C-Term

Fonction: Rabbit anti-MCAK Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 675 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KIF2C

Antigène: KIF2C (Kinesin Family Member 2C (KIF2C))

Autre désignation: MCAK

Sujet: Background: Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division.

ID gène: 11004

NCBI Accession: NP_006836

UniProt: Q99661

Pathways: Dynamique des Microtubules