PAGR1 anticorps (AA 1-50)

N° du produit ABIN7451928

Détail du produit anti-PAGR1 anticorps

Antigène: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Épitope: AA 1-50

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAGR1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-PA1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PAGR1

Antigène: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Autre désignation: PA1 (PAGR1 Produits)

Synonymes: anticorps C16orf53, anticorps C25H16orf53, anticorps PA1, anticorps 2900092E17Rik, anticorps C77040, anticorps PAGR1, anticorps GAS, anticorps Pa1, anticorps PAXIP1 associated glutamate rich protein 1, anticorps PAXIP1 associated glutamate rich protein 1A, anticorps Paxip1-associated glutamate-rich protein 1, anticorps PAGR1, anticorps Pagr1a, anticorps Pagr1

Sujet: Background: PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.

ID gène: 79447

NCBI Accession: NP_078792

UniProt: Q9BTK6