PDE8B anticorps (AA 835-885)

N° du produit ABIN7451947

Détail du produit anti-PDE8B anticorps

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Épitope: AA 835-885

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8B est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-PDE8B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 835 and 885

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PDE8B

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Autre désignation: PDE8B (PDE8B Produits)

Synonymes: anticorps PDE8B, anticorps ADSD, anticorps PPNAD3, anticorps B230331L10Rik, anticorps C030047E14Rik, anticorps RNPDE8B, anticorps phosphodiesterase 8B, anticorps high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, anticorps PDE8B, anticorps LOC100468338, anticorps pde8b, anticorps Pde8b

Sujet: Background: Phosphodiesterase 8B is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. PDE8B, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in the PDE8B gene are a cause of autosomal dominant striatal degeneration (ADSD) [taken from NCBI Entrez Gene (Gene ID: 8622)].

ID gène: 8622

NCBI Accession: NP_003710

UniProt: O95263

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process