PKD2 anticorps (AA 918-968)

N° du produit ABIN7451972

L’anticorps anti-PKD2 Polyclonal Lapin est utilisé pour la détection de PKD2 dans des échantillons de Humain et Souris. Il a été validé pour WB et IP.

Aperçu rapide pour PKD2 anticorps (AA 918-968) (ABIN7451972)

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-PKD2 anticorps

Épitope: AA 918-968

Fonction: Rabbit anti-Polycystin-2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 918 and 968

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PKD2

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Autre désignation: Polycystin-2

Sujet: Background: Polycystin-2 is a calcium permeable cation channel. Defects in the Polycystin-2 gene, PKD2, are the cause of polycystic kidney disease autosomal dominant type 2 (ADPKD2) which is characterized by progressive formation and enlargement of cysts in both kidneys, typically leading to end-stage renal disease in adult life. Cysts also occur in the liver and other organs [taken from the Universal Protein Resource (UniProt) Q13563].

ID gène: 5311

NCBI Accession: NP_000288

UniProt: Q13563

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity